State-of-the-art spherical polymer for highest demands in solid phase extraction. PS/DVB copolymer with quaternary ammonium modification for mixed-mode SPE with strong anion exchange and reversed-phase properties (MAX). Exchange capacity 0.25 meq/g, pKa ~ 18 and RP capacity 350 mg/g (caffeine in water). High-purity material with ideal flow properties and highest reproducibility. Allows highest reproducibility with extremely low blind values due to an optimized production process. Outstanding recovery rates especially for the enrichment of acidic (acids with pKa 2–8) analytes.